MARIOS AGELOPOULOS, PhD, Biomedical Research Foundation of the Academy of Athens, Athens
MYCN Amplifications and Metabolic Rewiring in Neuroblastoma
Marialena Pouliou, Marianna A Koutsi, Lydia Champezou, Angeliki-Ioanna Giannopoulou, Giannis Vatsellas, Christina Piperi, Marios Agelopoulos
Cancers (Basel) (2023)
https://pubmed.ncbi.nlm.nih.gov/37835497/
The Causes and Consequences of Spatial Organization of the Genome in Regulation of Gene Expression
Marios Agelopoulos, Spyros Foutadakis, and Dimitris Thanos
Frontiers in Immunology (2021)
https://www.frontiersin.org/journals/immunology
Typical Enhancers, Super-Enhancers, and Cancers
Marianna A Koutsi , Marialena Pouliou, Lydia Champezou, Giannis Vatsellas, Angeliki-Ioanna Giannopoulou , Christina Piperi , Marios Agelopoulos
Cancers (Basel) (2022)
https://pubmed.ncbi.nlm.nih.gov/36139535/
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YIORGOS APIDIANAKIS, PhD, Department of Biological Sciences, University of Cyprus
The bacterial metabolite 2-aminoacetophenone promotes association of pathogenic bacteria with flies.
Kapsetaki SE, Tzelepis I, Avgousti K, Livadaras I, Garantonakis N, Varikou K, Apidianakis Y.
Nature Communications (2014)
https://www.ncbi.nlm.nih.gov/pubmed/25043228
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DIMITRIS BEIS, PhD, Biomedical Research Foundation of the Academy of Athens, Athens
Reactivation of Notch Signaling Is Required for Cardiac Valve Regeneration
Kefalos, P., Agalou, A., Kawakami, K. and Beis D.
Scientific Reports (2019)
https://www.ncbi.nlm.nih.gov/pubmed/31690782
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CHRISTOS DELIDAKIS, PhD, Department of Biology, University of Crete, (IMBB-FORTH), Crete
The two Tribolium E(spl) genes show evolutionarily conserved expression and function during embryonic neurogenesis.
Kux K, Kiparaki M, Delidakis C.
Mechanism of Development (2013)
https://www.ncbi.nlm.nih.gov/pubmed/23485410
The Role of Insulators in Transgene Transvection in Drosophila.
Piwko P., Vitsaki I., Livadaras I., Delidakis C.
Genetics (2019)
https://www.ncbi.nlm.nih.gov/pubmed/30948430
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GEORGE DIALLINAS, PhD, Department of Biology, School of Science, University of Athens
Golgi-Bypass Is a Major Unconventional Route for Translocation to the Plasma Membrane of Non – Apical Membrane Cargoes in Aspergillus nidulans
Sofia Dimou, Mariangela Dionysopoulou, Georgia Maria Sagia, George Diallinas
Front Cell Developmental Biology (2022)
https://www.ncbi.nlm.nih.gov/pubmed/23485410
Profile of Membrane Cargo Trafficking Proteins and Transporters Expressed under N Source Derepressing Conditions in Aspergillus nidulans
Dimou S, Georgiou X, Sarantidi E, Diallinas G, Anagnostopoulos AK.
J Fungi (Basel) (2021)
https://pubmed.ncbi.nlm.nih.gov/35465316/
Transporter membrane traffic and function: lessons from a mould.
Diallinas G., Martzoukou O.
FEBS J. (2019)
https://www.mdpi.com/2309-608X/7/7/560
Secretory Vesicle Polar Sorting, Endosome Recycling and Cytoskeleton Organization Require the AP-1 Complex in Aspergillus nidulans.
Martzoukou O, Diallinas G, Amillis S.
Genetics (2018)
https://www.ncbi.nlm.nih.gov/pubmed/29925567
The AP-2 complex has a specialized clathrin-independent role in apical
endocytosis and polar growth in fungi.
Martzoukou O, Amillis S, Zervakou A, Christoforidis S, Diallinas G.
Elife (2017)
https://www.ncbi.nlm.nih.gov/pubmed/28220754
BsdABsd2-dependent vacuolar turnover of a misfolded version of the UapA transporter along the secretory pathway: prominent role of selective autophagy.
Minoas Evangelinos, Olga Martzoukou, Koar Chorozian, Sotiris Amillis and George Diallinas.
Molecular Microbiology (2016)
https://www.ncbi.nlm.nih.gov/pubmed/26917498
Oligomerization of the UapA Purine Transporter Is Critical for ER-Exit, Plasma Membrane Localization and Turnover.
J Mol Biol. (2015)
Martzoukou O, Karachaliou M, Yalelis V, Leung J, Byrne B, Amillis S, Diallinas G.
https://www.ncbi.nlm.nih.gov/pubmed/26049015
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ANTIGONI DIMAS, PhD, BSRC “Alexander Fleming”, Athens
Perturbations of genes essential for Müllerian duct and Wölffian duct development in Mayer-Rokitansky-Küster-Hauser syndrome
Na Chen, Sen Zhao, Angad Jolly, Lianlei Wang, Hongxin Pan, Jian Yuan, Shaoke Chen, Andre Koch, Congcon Ma, Weijie Tian, Ziqi Jia, Jia Kang, Lina Zhao, Chenglu qin, Xin Fan, Katharina Rall, Zeynep Coban-Akdemir, Zefu Chen, Shalini Jhangiani, Ze Liang, Ychen Niu, Xiaoxin Li, Zihui Yan, Yong Wu, Shuangshuang Dong, Chengcheng Song, Guixin Qiu, Ahuyang Zhang, Pengfei Liu, Jennifer E Posey, Feng Zhang, Guangnan Luo, Zhihong Wu, Deciphering Disorders Involving Scoliosis and Comorbidities (DISCO) study group; Jianzhong Su, Jianguo Zhang, Eugenia Y Chen, Konstantinos Rouskas, Stavros Glentis, Flora Bacopoulou, Efthymios Deligeoroglou, George Chrousos, Stanislas Lyonnet, Michel Polak, Carla Rosenberg, Irene Dingeldein, Ximena Bonilla, Christelle Borel, Richard A Gibbs, Jennifer E Dietrich, Antigone S Dimas, Stylianos E Antonarakis, Sara Y Brucker, James R Lupski, Nan Wu, Lan Zhu.
The American Journal of Human Genetics (2021)
https://pubmed.ncbi.nlm.nih.gov/33434492/
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VASSILIS DOURIS, Department of Biological Applications and Technology, University of Ioannina, Ioannina
“What I cannot create, I do not understand”: functionally validated synergism of metabolic and target site insecticide resistance
George-Rafael Samantsidis, Rafaela Panteleri, Shane Denecke1, Stella Kounadi1, Iason Christou, Ralf Nauen, Vassilis Douris, and John Vontas
Proc Biol Sci. (2020)
Using CRISPR/Cas9 genome modification to understand the genetic basis of insecticide resistance: Drosophila and beyond
Vassilis Douris, Shane Denecke, Thomas Van Leeuwen, Chris Bass, Ralf Nauen, John Vontas
ELSEVIE (2020)
https://pubmed.ncbi.nlm.nih.gov/32527434/
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EPAMINONDAS DOXAKIS, PhD, Biomedical Research Foundation of the Academy of Athens, Athens
Unraveling the Pathways to Neuronal Homeostasis and Disease: Mechanistic Insights Into the Role of RNA-Binding Proteins and Associated Factors
Stylianos Ravanidis, Fedon-Giasin Kattan, Epaminondas Doxakis
Int J Mol Sci (2018)
https://pubmed.ncbi.nlm.nih.gov/30081499
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ARISTIDES G. ELIOPOULOS, PhD, Department of Biology, Medical School,National & Kapodistrian University of Athens
Polycomb Repressor Complex 2 in Genomic Instability and Cancer
Zoe Veneti, Kalliopi K. Gkouskou, and Aristides G. Eliopoulos
International Journal of Molecular Sciences (2017)
https://www.ncbi.nlm.nih.gov/pubmed/28758948
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GEORGIA GREGORIOU, PhD, Faculty of Medicine, University of Crete
Distinct roles of prefrontal and parietal areas in the encoding of attentional priority.
Sapountzis P, Paneri S, Gregoriou GG
PNAS U S A (2018)
https://www.ncbi.nlm.nih.gov/pubmed/30154164
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ARTEMIS HATZIGEORGIOU, PhD, Department of Computer and Communications Engineering, University of Thessaly
DIANA-mirExTra v2.0: Uncovering microRNAs and transcription factors with crucial roles in NGS expression data.
Vlachos IS, Vergoulis T, Paraskevopoulou MD, Lykokanellos F, Georgakilas G, Georgiou P, Chatzopoulos S, Karagkouni D, Christodoulou F, Dalamagas T, Hatzigeorgiou AG.
Nucleic Acid Research (2016)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987956
DIANA-LncBase v2: indexing microRNA targets on non-coding transcripts
Maria D. Paraskevopoulou, Ioannis S. Vlachos, Dimitra Karagkouni, Georgios Georgakilas, Ilias Kanellos, Thanasis Vergoulis, Konstantinos Zagganas, Panayiotis Tsanakas, Evangelos Floros, Theodore Dalamagas, and Artemis G. Hatzigeorgiou
Nucleic Acids Research (2016)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702897
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PANTELIS HATZIS, PhD, Institute of Molecular Biology and Genetics, BSRC “Alexander Fleming”, Athens
A Positive Regulatory Loop between a Wnt-Regulated Non-coding RNA and ASCL2 Controls Intestinal Stem Cell Fate.
Giakountis A, Moulos P, Zarkou V, Oikonomou C, Harokopos V, Hatzigeorgiou AG, Reczko M, Hatzis P.
Cell Press (2016)
https://www.ncbi.nlm.nih.gov/pubmed/27292638
Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF.
Jurian Schuijers, Michal Mokry, Pantelis Hatzis, Edwin Cuppen, and Hans Clevers
The Embo Journal (2014)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989608
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APOSTOLOS KLINAKIS, PhD, Biomedical Research Foundation of the Academy of Athens, Athens
KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis.
George Papafotiou, Varvara Paraskevopoulou, Eleni Vasilaki, Zoi Kanaki, Nikolaos Paschalidis, and Apostolos Klinakis
Nature Communications (2016)
https://www.ncbi.nlm.nih.gov/pubmed/27320313
A new tumor suppressor role for the Notch pathway in bladder cancer.
Rampias T, Vgenopoulou P, Avgeris M, Polyzos A, Stravodimos K, Valavanis C, Scorilas A, Klinakis A.
Nature Medicine (2014)
https://www.ncbi.nlm.nih.gov/pubmed/25194568
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ANGELIKI MAGKLARA, PHD, Faculty of Medicine, School of Life Sciences, University of Ioannina, Ioannina
The Histone Demethylase LSD1/ΚDM1A Mediates Chemoresistance in Breast Cancer via Regulation of a Stem Cell Program
John Verigos, Panagiotis Karakaidos, Dimitris Kordias, Alexandra Papadou-Bai, Zoi Evangelou, Haralampos V. Harissis, Apostolos Klinakis, Angeliki Mangklara.
Cancers (2019)
https://pubmed.ncbi.nlm.nih.gov/31627418
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REBECCA MATSAS, PHD, Hellenic Pasteur Institute, Athens
Defective Synaptic Connectivity and Axonal Neuropathology in a Human iPSC-based Model of Familial Parkinson’s Disease
Kouroupi, E. Taoufik, I. S. Vlachos, K. Tsioras, N. Antoniou, F. Papastefanaki, D. Chroni-Tzartou, W. Wrasidlo, D. Bohl, D. Stellas, P.K. Politis, K. Vekrellis, D. Papadimitriou, L. Stefanis, P. Bregestovski, A.G. Hatzigeorgiou, E. Masliah, R. Matsas
Proceedings of the National Academy of Sciences on the USA (2017)
https://pubmed.ncbi.nlm.nih.gov/28416701
MicroRNA-934 Is a Novel Primate-Specific Small Non-Coding RNA With Neurogenic Function During Early Development
Kanella Prodromidou, Ioannis S Vlachos, Maria Gaitanou, Georgia Kouroupi, Artemis G Hatzigeorgiou, Rebecca Matsas
eLife (2020)
https://pubmed.ncbi.nlm.nih.gov/32459171
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ILIAS MYLONIS, PhD, Laboratory of Biochemistry, Faculty of Medicine, University of Thessaly
Specific Inhibition of HIF Activity: Can Peptides Lead the Way?
Mylonis I , Chachami G, Simos G. Specific Inhibition of HIF Activity: Can Peptides Lead the
CANCERS (2021)
https://pubmed.ncbi.nlm.nih.gov/33499237/
Calcitriol Suppresses HIF-1 and HIF-2 Transcriptional Activity by Reducing HIF-1/2α Protein Levels via a VDR-Independent Mechanism
Gkotinakou IM, Kechagia E, Pazaitou-Panayiotou K, Mylonis I, Liakos P, Tsakalof A. Calcitriol Suppresses HIF-1 and HIF-2 Transcriptional Activity by Reducing HIF-1/2α Protein Levels via a VDR-Independent Mechanism. Cells. 2020;9(11):2440. Published 2020 Nov 9. doi:10.3390/cells9112440
CELLS (2020)
https://pubmed.ncbi.nlm.nih.gov/33182300/
HIF-1α-derived cell-penetrating peptides inhibit ERK-dependent activation of HIF-1 and trigger apoptosis of cancer cells under hypoxia.
Karagiota A, Kourti M, Simos G, Mylonis I.
CMLS (2018)
https://www.ncbi.nlm.nih.gov/pubmed/30535970
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JOSEPH (SIFIS) PAPAMATHEAKIS, PhD, School of Sciences, University of Crete, IMBB-FORTH, Crete
NF-Y and the immune response: Dissecting the complex regulation of MHC genes.
Sachini N, Papamatheakis J.
Biochim Biophys Acta. (2017)
https://www.ncbi.nlm.nih.gov/pubmed/27989934
Promyelocytic Leukemia Protein is an Essential Regulator of Stem Cell Pluripotency and Somatic Cell Reprogramming.
Hadjimichael C, Chanoumidou K, Nikolaou C, Klonizakis A, Theodosi GI, Makatounakis T, Papamatheakis J, Kretsovali A. Promyelocytic Leukemia Protein Is an Essential
Stem Cell Reports (2017)
https://doi.org/10.1016/j.stemcr.2017.03.006
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KATERINA PAPANIKOLOPOULOU, BSRC “Alexander Fleming”, Athens
Mical modulates Tau toxicity via cysteine oxidation in vivo
Engie Prifti, Eleni N Tsakiri, Ergina Vourkou, George Stamatakis, Martina Samiotaki, Efthimios M C Skoulakis and Katerina Papanikolopoulou
Acta Neuropathologica Communications (2022)
https://pubmed.ncbi.nlm.nih.gov/35379354/
The two Cysteines of Tau protein are functionally distinct and contribute differentially to its pathogenicity in vivo.
Engie Prifti, Eleni N. Tsakiri, Ergina Vourkou, George Stamatakis, Martina Samiotaki, Katerina Papanikolopoulou.
Journal of Neuroscience (2020)
https://pubmed.ncbi.nlm.nih.gov/33334867/
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MARIA ROUBELAKIS, PhD, Laboratory of Biology, School of Medicine, University of Athens
miR-26a Mediates Adipogenesis of Amniotic Fluid Mesenchymal Stem/Stromal Cells via PTEN, Cyclin E1, and CDK6.
Trohatou O, Zagoura D, Orfanos NK, Pappa KI, Marinos E, Anagnou NP, Roubelakis MG.
Stem Cells and Development (2017)
https://www.ncbi.nlm.nih.gov/pubmed/28068868
Mesenchymal Stem/Stromal Cells in Regenerative Medicine: Past, Present, and Future.
Trohatou O, Roubelakis MG.
Cell Reprogramming (2017)
https://www.ncbi.nlm.nih.gov/pubmed/28520465
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DESPINA SANOUDOU, PhD, Biomedical Research Foundation of the Academy of Athens, Athens
Impaired calcium homeostasis is associated with sudden cardiac death and arrhythmias in a genetic equivalent mouse model of the human HRC-Ser96Ala variant.
Tzimas C, Johnson DM, Santiago DJ, Vafiadaki E, Arvanitis DA, Davos CH, Varela A3, Athanasiadis NC, Dimitriou C, Katsimpoulas M, Sonntag S, Kryzhanovska M, Shmerling D, Lehnart SE, Sipido KR, Kranias EG, Sanoudou D.
Nucleic Acids Research (2016)
https://www.ncbi.nlm.nih.gov/pubmed/28859293
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INGA SIDEN-KIAMOS, PhD, IMBB-FORTH, Heraklion, Crete
Gene editing in Plasmodium berghei made easy: Development of a CRISPR/Cas9 protocol using linear donor template and ribozymes for sgRNA generation
Elena Deligianni, Inga Siden Kiamos
Mol Biochem Parasitol (2021)
https://pubmed.ncbi.nlm.nih.gov/34537287/
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EFTHIMIOS SKOULAKIS, PHD, Institute of Molecular Biology and Genetics, BSRC “Alexander Fleming”, Athens
Drosophila Bruton’s Tyrosine Kinase Regulates Habituation Latency and Facilitation in Distinct Mushroom Body Neurons.
Ilianna G. Roussou, Katerina Papanikolopoulou, Charalambos Savakis, E. M. C. Skoulakis
The Journal of Neuroscience (2019)
https://pubmed.ncbi.nlm.nih.gov/31530645
Temporally specific engagement of distinct neuronal circuits regulating olfactory habituation in Drosophila.
Semelidou O., Acevedo S.F., Skoulakis E.M.
Elife (2018)
https://www.ncbi.nlm.nih.gov/pubmed/30576281
The Drosophila Receptor Tyrosine Kinase Alk Constraints Long-Term Memory Formation.
Jean Y. Gouzi, Mikela Bouraimi, ILian G. Roussou, Anastasios Moressis, E.M.C. Skoulakis.
The Journal of Neuroscience (2018)
https://pubmed.ncbi.nlm.nih.gov/30030398/
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GEORGIA SOTIROPOULOU, PhD, Department of Pharmacy, School of Health Sciences, University of Patras
KLK6 proteolysis is implicated in the turnover and uptake of extracellular alpha-synuclein species.
Pampalakis G, Sykioti V-S, Ximerakis M, Stefanakou-Kalakou I, Melki R, Vekrellis K, Sotiropoulou G.
Oncotarget (2017)
https://www.ncbi.nlm.nih.gov/pubmed/27845893
Resistance of naturally secreted alpha-synuclein to proteolysis.
Ximerakis M, Pampalakis G, Roumeliotis TI, Sykioti V-S, Garbis SD, Stefanis L, Sotiropoulou G, Vekrellis K.
FASEB Journal (2014)
https://www.ncbi.nlm.nih.gov/pubmed/24723692
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CHARALAMPOS G. SPILIANAKIS, University of Crete, (IMBB-FORTH), Heraklion, Crete
SATB1-mediated chromatin landscape in T cells.
Zelenka T & Spilianakis C.G.
Nucleus (2020)
https://pubmed.ncbi.nlm.nih.gov/33356851
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CONSTANTINOS STATHOPOULOS, PhD, Department of Biochemistry, School of Medicine, University of Patras
Direct modulation of T-box riboswitch-controlled transcription by protein synthesis inhibitors.
Vassiliki Stamatopoulou, Maria Apostolidi, Shuang Li, Katerina Lamprinou, Athanasios Papakyriakou, Jinwei Zhang, and Constantinos Stathopoulos
Nucleic Acid Research (2017)
https://www.ncbi.nlm.nih.gov/pubmed/28973457
The complex evolutionary history of aminoacyl-tRNA synthetases.
Chaliotis A, Vlastaridis P, Mossialos D, Ibba M, Becker HD, Stathopoulos C, Amoutzias GD.
Nucleic Acid Research (2017)
https://www.ncbi.nlm.nih.gov/pubmed/28180287
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STAVROS TARAVIRAS, PhD, School of Medicine, University of Patras
Geminin prevents DNA damage in vagal neural crest cells to ensure normal enteric neurogenesis.
Konstantinidou C, Taraviras S, Pachnis V.
BMC Biology (2016)
https://www.ncbi.nlm.nih.gov/pubmed/27776507
Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis.
Stathopoulou A, Natarajan D, Nikolopoulou P, Patmanidi AL, Lygerou Z, Pachnis V, Taraviras S.
Developmental Biology (2016)
https://www.ncbi.nlm.nih.gov/pubmed/26658318
Concise Review: Geminin-A Tale of Two Tails: DNA Replication and Transcriptional/Epigenetic Regulation in Stem Cells.
Patmanidi AL, Champeris Tsaniras S, Karamitros D, Kyrousi C,
Lygerou Z, Taraviras S.
Stem Cells (2017)
https://www.ncbi.nlm.nih.gov/pubmed/27859962
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GEORGE ZACHOS, PhD, Department of Biology, University of Crete
The abscission checkpoint senses chromatin bridges through Top2α recruitment to DNA knots.
Eleni Petsalaki, Sofia Balafouti, Athina A. Kyriazi, George Zachos
J Cell Biol (2023) 222 (11): e202303123
https://doi.org/10.1083/jcb.202303123
An ATM-Chk2-INCENP pathway activates the abscission checkpoint
Eleni Petsalaki, George Zachos
JCB-Journal of Cell Biology (2020)
PMID: 33355621 – PMCID: PMC7769160
https://pubmed.ncbi.nlm.nih.gov/33355621
DNA damage response proteins regulating mitotic cell division: double agents preserving genome stability.
Petsalaki E, Zachos G.
The FEBS Journal (2020)
https://www.ncbi.nlm.nih.gov/pubmed/32027459
Building bridges between chromosomes: novel insights into the abscission checkpoint.
Petsalaki E, Zachos G.
CMLS (2019)
https://www.ncbi.nlm.nih.gov/pubmed/31302750
Src activation by Chk1 promotes actin patch formation and prevents chromatin bridge breakage in cytokinesis.
Dandoulaki M, Petsalaki E, Sumpton D, Zanivan S, Zachos G.
Journal of Cell Biology (2018)
https://www.ncbi.nlm.nih.gov/pubmed/29954829
Chmp4c is required for stable kinetochore-microtubule attachments.
Petsalaki E, Dandoulaki M, Zachos G.
Chromosoma (2018)
https://www.ncbi.nlm.nih.gov/pubmed/29968190
Clks 1,2 and 4 prevent chromatin breakage by regulating the AuroraB-dependent abscission checkpoint.
Petsalaki E, Zachos G.
Nature Communications (2016)
https://www.ncbi.nlm.nih.gov/pubmed/27126587
Novel ESCRT functions at kinetochores.
Petsalaki E and Zachos G. Novel ESCRT functions at kinetochores.
Aging (2018)
https://www.ncbi.nlm.nih.gov/pubmed/29562220
The ESCRT protein Chmp4c regulates mitotic spindle checkpoint signaling.
Petsalaki E, Dandoulaki M and Zachos G.
Journal of Cell Biology (2018)
https://www.ncbi.nlm.nih.gov/pubmed/29362225
Clks 1, 2 and 4 prevent chromatin breakage by regulating the Aurora B-dependent abscission checkpoint.
Petsalaki E and Zachos G.
Nature Communications (2016).
https://www.ncbi.nlm.nih.gov/pubmed/27126587
Chk1 protects against chromatin bridges by constitutively phosphorylating BLM serine 502 to inhibit BLM degradation.
Petsalaki E, Dandoulaki M, Morrice N and Zachos G.
Journal of Cell Science (2014).
https://www.ncbi.nlm.nih.gov/pubmed/25015292
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LASKARO ZAGORAIOU, Biomedical Research Foundation of the Academy of Athens, Athens
Pitx2cholinergic interneurons are the source of C bouton synapses on brainstem motor neurons
Rozani I, Tsapara G, Witts EC, Deaville SJ, Miles GB, Zagoraiou L.
Free PMC Article (2019)
https://pubmed.ncbi.nlm.nih.gov/30894556/
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CHRISTOS ZERVAS, PhD, Biomedical Research Foundation of the Academy of Athens, Athens
IPP Complex Reinforces Adhesion by Relaying Tension-Dependent Signals to Inhibit Integrin Turnover.
Vakaloglou KM, Chrysanthis G, Rapsomaniki MA, Lygerou Z, Zervas CG.
Cell Reports (2016)
https://pubmed.ncbi.nlm.nih.gov/26972014/
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GEORGINA XANTHOU, PhD, Biomedical Research Foundation of the Academy of Athens, Athens
Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T
cells that restrain asthmatic responses.
Tousa S, Semitekolou M, Morianos I, Banos A, Trochoutsou AI, Brodie TM, Poulos N, Samitas K, Kapasa M, Konstantopoulos D, Paraskevopoulos G, Gaga M, Hawrylowicz CM, Sallusto F, Xanthou G.
PNAS (2017)
https://www.ncbi.nlm.nih.gov/pubmed/28320933
Activin-A is overexpressed in severe asthma and is implicated inangiogenic processes.
Samitas K, Poulos N, Semitekolou M, Morianos I, Tousa S, Economidou E, Robinson DS, Kariyawasam HH, Zervas E, Corrigan CJ, Ying S, Xanthou G,
Gaga M.
European Respiratory Journal (2016)
https://www.ncbi.nlm.nih.gov/pubmed/26869672
Tolerogenic signaling by pulmonary CD1c+ dendritic cells induces
regulatory T cells in patients with chronic obstructive pulmonary disease
by IL-27/IL-10/inducible costimulator ligand.
Tsoumakidou M, Tousa S, Semitekolou M, Panagiotou P, Panagiotou A, Morianos I, Litsiou E, Trochoutsou AI, Konstantinou M, Potaris K, Footitt J, Mallia P, Zakynthinos S, Johnston SL, Xanthou G.
The Journal of Allergy and Clinical Immunology (2014)
https://www.ncbi.nlm.nih.gov/pubmed/25051954
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